Using brain stimulation to improve cognitive function in schizophrenia
Theta burst modulation of hippocampal-cortical rhythms in schizophrenia
This study is looking at whether a special type of brain stimulation called theta burst stimulation can help improve thinking and memory problems in people with schizophrenia, like disorganized thoughts and hallucinations, by targeting important areas of the brain.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11113636 on NIH RePORTER |
What this research studies
This research investigates how theta burst stimulation (TBS), a form of brain stimulation, can enhance the functioning of the hippocampus, which is crucial for cognitive processes. By targeting specific areas of the brain, the study aims to understand if TBS can improve cognitive deficits associated with schizophrenia, such as disorganized thought and hallucinations. The approach combines both invasive and non-invasive techniques to assess changes in brain activity and cognitive performance in patients with schizophrenia. Participants may undergo brain stimulation sessions while their brain activity is monitored to evaluate the effects on cognitive function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with schizophrenia who experience cognitive deficits.
Not a fit: Patients with schizophrenia who do not exhibit cognitive deficits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that significantly improve cognitive function and quality of life for individuals with schizophrenia.
How similar studies have performed: Previous research has shown promising results with brain stimulation techniques in improving cognitive function in various neurological conditions, suggesting potential for success in this novel application.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Solomon, Ethan — Stanford University
- Study coordinator: Solomon, Ethan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.