Using blood tests to quickly detect and monitor cancers with FGFR changes
Liquid Biopsy for Rapid Detection and Real Time Monitoring of FGFR-altered Cancers
['FUNDING_OTHER'] · OHIO STATE UNIVERSITY · NIH-10930924
This study is testing a new blood test that can quickly find changes in a specific gene related to cancer, helping doctors better tailor treatments for patients and keep track of how well those treatments are working.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OHIO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (Columbus, UNITED STATES) |
| Trial ID | NIH-10930924 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a liquid biopsy method to rapidly identify and monitor cancers that have alterations in the fibroblast growth factor receptor (FGFR). By analyzing cell-free DNA from blood samples, the study aims to provide a non-invasive way to detect FGFR gene changes, which can help qualify patients for targeted therapies and monitor their response to treatment. This approach addresses the challenge of resistance that many patients face when undergoing FGFR inhibitor treatments. The goal is to improve patient outcomes by enabling timely adjustments to therapy based on real-time monitoring of cancer progression.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with advanced cancers that exhibit FGFR alterations, such as bladder cancer or cholangiocarcinoma.
Not a fit: Patients whose cancers do not involve FGFR alterations or those with early-stage cancers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with FGFR-altered cancers.
How similar studies have performed: Other research has shown promise in using liquid biopsies for cancer detection and monitoring, indicating that this approach could be effective for FGFR-altered cancers as well.
Where this research is happening
Columbus, UNITED STATES
- OHIO STATE UNIVERSITY — Columbus, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROYCHOWDHURY, SAMEEK — OHIO STATE UNIVERSITY
- Study coordinator: ROYCHOWDHURY, SAMEEK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Advanced Cancer, Bladder Cancer