Using biomarkers to improve heart health after non-cardiac surgery
Official title: Post-Operative Biomarker-Guided Precision Medicine for Cardiovascular Risk Reduction
Funded at New York University School of Medicine · NIH-11057831 · Data updated 2026-11-12
This study is looking at patients having non-heart surgeries to see if they have any hidden heart problems, and it will test personalized treatments to help keep their hearts healthy during recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | April 21, 2025 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $392,037 |
| NIH project number | 1R34HL173301-01A1 |
| Project ID | NIH-11057831 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals scheduled for non-cardiac surgeries who may have underlying cardiovascular conditions.
✕Less likely to help
Patients who are not undergoing non-cardiac surgeries or those without any cardiovascular risk factors may not benefit from this research.
What this research studies
This research focuses on patients undergoing non-cardiac surgery who may have hidden cardiovascular issues. By monitoring specific biomarkers during and after surgery, the study aims to identify those at risk for heart complications. The approach involves a future clinical trial that will test the effectiveness of personalized treatment plans, including low-dose anticoagulants and high-intensity statins, to enhance heart health outcomes. Patients will be monitored for myocardial injury, which can indicate potential long-term cardiovascular risks.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies for heart complications in patients after non-cardiac surgeries.
How similar studies have gone: Previous research has shown promise in using biomarkers for cardiovascular risk assessment, indicating potential for success in this novel approach.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Smilowitz, Nathaniel Rosso — New York University School of Medicine
- Study coordinator: Smilowitz, Nathaniel Rosso
Related research
Other NIH-funded projects on the same topics.
-
Cardiovascular risk planning and reduction for men with prostate cancer
A program to better predict and reduce heart disease risk in men treated for prostate cancer, especially older patients.
-
Traumatic Stress, Epigenetic Aging, and Heart Risk in Veterans
A large study using Veterans Affairs data to see if traumatic stress and faster biological aging relate to higher risk of stroke and heart disease.
-
Lifestyle plan to protect muscle and heart health for adults with obesity using GLP-1 medications
A real-world trial tests a combined nutrition and resistance-training program versus standard care for adults starting GLP-1 weight loss drugs to preserve lean mass and cardiovascular health.
-
Role of the body's natural cannabis-like system in diabetes progression and heart risk
This grant studies how the body's endocannabinoid system affects the progression from obesity to diabetes and the associated risk for cardiovascular disease in adults.
-
Community and Peer Support for Reducing Cardiovascular Risk
Aims to understand how community and peer programs can help people lower cardiovascular risk, by analyzing existing programs and how their implementation and social support influence outcomes.
-
CardioPredict ML: A smarter way to gauge heart risk before pregnancy
A machine learning tool helps identify women at risk for pregnancy-related heart problems before conception, using health records and prior pregnancy data.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.