Using big data to improve medication safety for pregnant patients
Official title: Big data apprOaches fOr Safe Therapeutics in Healthy Pregnancies (BOOST-HP)
Funded at Harvard Pilgrim Health Care, INC. · NIH-11082300 · Data updated 2026-11-12
This study is looking at how safe certain medications are for pregnant women by using advanced data analysis to quickly find important information, so that moms-to-be and their doctors can make better decisions about what medications to use.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Pilgrim Health Care, INC. NIH-funded |
| Lab location | 1 site (Canton, UNITED STATES) |
| Project start | August 29, 2022 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $613,261 |
| NIH project number | 5R01HD110107-04 |
| Project ID | NIH-11082300 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant individuals who are currently using or considering medications during their pregnancy.
✕Less likely to help
Patients who are not pregnant or those who are not using any medications during pregnancy may not receive benefits from this research.
What this research studies
This research investigates the safety of medications used during pregnancy by leveraging big data analytics. It aims to accelerate the generation of evidence regarding the risks and benefits of these medications, which currently takes an average of 27 years. The approach involves data-mining techniques to identify potential safety signals and evaluate them in a structured manner. By focusing on vulnerable populations, the research seeks to provide more accurate and timely information for pregnant patients and their healthcare providers.
Why it matters
Potential benefit: If successful, this research could lead to safer medication use during pregnancy, ultimately improving health outcomes for both mothers and their babies.
How similar studies have gone: Previous research utilizing big data approaches in pharmacovigilance has shown promise, indicating that this methodology could yield significant insights into medication safety during pregnancy.
Where this research is happening
-
Harvard Pilgrim Health Care, INC.
Canton, United States Active
Researchers
- Principal investigator: Maro, Judith — Harvard Pilgrim Health Care, INC.
- Study coordinator: Maro, Judith
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.