Using bag-mask ventilation to prevent low oxygen levels during intubation in emergency situations.
Official title: Bag-Mask Ventilation to PreVent Hypoxemia during Tracheal Intubation in the Emergency Department: A Clinical Trial
Funded at Vanderbilt University Medical Center · NIH-10914977 · Data updated 2026-11-12
This study is looking at how well using a bag-mask to help patients breathe can prevent low oxygen levels during intubation in the emergency room, and it's aimed at helping critically ill adults who need breathing support.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | August 1, 2020 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $166,677 |
| NIH project number | 5K23HL153584-05 |
| Project ID | NIH-10914977 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are critically ill adults who require intubation in emergency department settings.
✕Less likely to help
Patients who are not critically ill or do not require intubation may not benefit from this research.
What this research studies
This research investigates the effectiveness of bag-mask ventilation in preventing hypoxemia during tracheal intubation in emergency department settings. The study aims to adapt methodologies from intensive care to the fast-paced environment of emergency care, focusing on critically ill adults who require mechanical ventilation. By comparing outcomes in patients receiving bag-mask ventilation versus those who do not, the research seeks to improve patient safety and outcomes during a critical procedure. The principal investigator, Dr. Jonathan Casey, is dedicated to enhancing the quality of emergency care through innovative trial designs.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of hypoxemia and other complications during intubation in emergency settings, leading to better patient outcomes.
How similar studies have gone: Previous studies in intensive care have shown that bag-mask ventilation can prevent hypoxemia, but this research aims to determine if those findings apply in emergency departments, making it a novel approach.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Casey, Jonathan Dale — Vanderbilt University Medical Center
- Study coordinator: Casey, Jonathan Dale
Related research
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Pre-intubation checklist to make emergency breathing tube placement safer for injured children
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.