Using B cells to improve recovery from acute respiratory distress syndrome (ARDS)
B cells for treatment of ARDS
This study is looking at how special immune cells called B cells might help people recovering from acute respiratory distress syndrome (ARDS) by reducing inflammation and helping the lungs and brain heal.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11175768 on NIH RePORTER |
What this research studies
This research investigates how B cells can be used to treat patients recovering from acute respiratory distress syndrome (ARDS), particularly focusing on the pulmonary and neurological complications that can arise after the condition. The study utilizes a mouse model to explore how B cells can be administered to reduce inflammation and promote healing in the lungs and brain. By understanding how these B cells migrate to areas of injury, the research aims to develop a therapy that could restore immune balance and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who have experienced ARDS and are facing ongoing pulmonary or neurological issues.
Not a fit: Patients who have not experienced ARDS or those with other unrelated respiratory conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly enhance recovery and reduce long-term complications for ARDS survivors.
How similar studies have performed: Previous research has shown promise in using B cell therapies for inflammatory conditions, suggesting potential success for this novel approach in ARDS.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Hanidziar, Dusan — Massachusetts General Hospital
- Study coordinator: Hanidziar, Dusan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.