Using air filters to slow heart disease progression
Slowing Atherothrombosis Progression through Indoor Air Filtration: A Crossover Trial in Hispanic and non-Hispanic Adults with Ischemic Heart Disease History
['FUNDING_R01'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-10854852
This study is looking at whether using affordable air purifiers at home can help lower harmful air pollution and improve heart health for people with a history of heart disease, including both Hispanic and non-Hispanic adults.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-10854852 on ClinicalTrials.gov |
What this research studies
This research investigates how using indoor air filtration can reduce fine particulate pollution (PM2.5) exposure and its impact on heart disease progression. Participants will use low-cost air purifiers in their homes, and the study will measure changes in various heart disease biomarkers over time. The trial will include diverse groups of Hispanic and non-Hispanic adults with a history of ischemic heart disease, focusing on both immediate and long-term effects of air filtration on cardiovascular health.
Who could benefit from this research
Good fit: Ideal candidates are Hispanic and non-Hispanic adults with a history of ischemic heart disease living in areas with high levels of air pollution.
Not a fit: Patients without a history of ischemic heart disease or those living in areas with low air pollution may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved heart health and reduced risk of cardiovascular events for patients exposed to harmful air pollutants.
How similar studies have performed: Previous studies have shown promising short-term benefits of air filtration on cardiovascular health, but this is one of the first to assess long-term effects.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHEN, ZHANGHUA — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: CHEN, ZHANGHUA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease