Using air filters to slow heart disease progression
Official title: Slowing Atherothrombosis Progression through Indoor Air Filtration: A Crossover Trial in Hispanic and non-Hispanic Adults with Ischemic Heart Disease History
Funded at University of Southern California · NIH-10854852 · Data updated 2026-11-12
This study is looking at whether using affordable air purifiers at home can help lower harmful air pollution and improve heart health for people with a history of heart disease, including both Hispanic and non-Hispanic adults.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | September 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $655,513 |
| NIH project number | 5R01ES033707-03 |
| Project ID | NIH-10854852 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are Hispanic and non-Hispanic adults with a history of ischemic heart disease living in areas with high levels of air pollution.
✕Less likely to help
Patients without a history of ischemic heart disease or those living in areas with low air pollution may not benefit from this research.
What this research studies
This research investigates how using indoor air filtration can reduce fine particulate pollution (PM2.5) exposure and its impact on heart disease progression. Participants will use low-cost air purifiers in their homes, and the study will measure changes in various heart disease biomarkers over time. The trial will include diverse groups of Hispanic and non-Hispanic adults with a history of ischemic heart disease, focusing on both immediate and long-term effects of air filtration on cardiovascular health.
Why it matters
Potential benefit: If successful, this research could lead to improved heart health and reduced risk of cardiovascular events for patients exposed to harmful air pollutants.
How similar studies have gone: Previous studies have shown promising short-term benefits of air filtration on cardiovascular health, but this is one of the first to assess long-term effects.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Chen, Zhanghua — University of Southern California
- Study coordinator: Chen, Zhanghua
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.