Using AI to identify depression and anxiety in patients with heart disease or diabetes

Leveraging Large Language Models and Machine Learning Algorithms to Assess Depression and Anxiety Symptoms and Risks for Patients with Cardiovascular Disease or Diabetes Mellitus

NIH-funded research Stanford University · NIH-10949395

This study is looking at how smart computer programs can help find signs of depression and anxiety in people with heart disease or diabetes by analyzing their messages to their doctors, so we can better understand and support their mental health needs.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10949395 on NIH RePORTER

What this research studies

This research investigates how advanced AI algorithms can analyze patient messages to identify symptoms of depression and anxiety in individuals with cardiovascular disease or diabetes. By examining over 46 million messages from a patient portal, the study aims to uncover the hidden mental health needs of these patients, which are often overlooked during routine medical visits. The approach combines large language models and machine learning to enhance understanding and prediction of mental health risks in this population. Ultimately, the goal is to improve diagnosis and treatment pathways for co-morbid conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with cardiovascular disease or diabetes who may also be experiencing symptoms of depression or anxiety.

Not a fit: Patients without cardiovascular disease or diabetes, or those who do not exhibit symptoms of depression or anxiety, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better identification and management of depression and anxiety in patients with cardiovascular disease or diabetes, improving their overall health outcomes.

How similar studies have performed: Other research has shown promise in using AI and machine learning to address mental health issues, indicating that this approach could be effective in this context as well.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Anxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.