Using advanced MRI to predict treatment response in patients with brain artery disease
Longitudinal and quantitative MR plaque imaging for prediction of response to medical management in symptomatic intracranial atherosclerosis
['FUNDING_R01'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-10579278
This study is looking at how special MRI scans can help us see changes in the fatty deposits in the brain's arteries, so we can better understand which patients might need different treatments for their condition.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-10579278 on ClinicalTrials.gov |
What this research studies
This research investigates how advanced magnetic resonance imaging (MRI) can be used to visualize and assess changes in atherosclerotic plaques in the arteries of the brain. By focusing on the characteristics of these plaques, the study aims to identify patients who may not respond well to standard medical treatments for intracranial atherosclerotic disease (ICAD). The approach involves high-resolution imaging techniques that can capture detailed information about plaque features over time, potentially leading to more personalized treatment strategies. Patients will undergo MRI scans to monitor their condition and help determine the best course of action for their care.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with symptomatic intracranial atherosclerotic disease who are at risk for recurrent strokes.
Not a fit: Patients with non-atherosclerotic causes of stroke or those who do not have symptomatic intracranial atherosclerotic disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients with intracranial atherosclerotic disease, reducing the risk of recurrent strokes.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques to assess vascular conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FAN, ZHAOYANG — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: FAN, ZHAOYANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease, atherosclerotic disease, atherosclerotic vascular disease