Using advanced MRI to assess blood flow and tissue health in scleroderma patients
Official title: Evaluation of digital ischemia in scleroderma with multiparametric MRI
Funded at Yale University · NIH-10984568 · Data updated 2026-11-12
This study is looking at how special MRI scans can help us understand blood flow and tissue health in people with scleroderma, so we can find better ways to manage the complications that affect their daily lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $173,216 |
| NIH project number | 1K23HL168223-01A1 |
| Project ID | NIH-10984568 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with scleroderma who experience symptoms related to digital ischemia or have a history of digital ulcerations.
✕Less likely to help
Patients with scleroderma who do not exhibit symptoms of digital ischemia or related complications may not benefit from this research.
What this research studies
This research investigates how multiparametric MRI can be used to evaluate blood flow and tissue health in patients with scleroderma, a chronic autoimmune disease. The study aims to develop quantitative imaging biomarkers that can provide a more accurate assessment of complications like digital ischemia and fibrosis, which significantly impact patients' quality of life. By correlating these MRI findings with clinical assessments, the research seeks to improve monitoring and treatment strategies for scleroderma. Patients will undergo MRI scans to help identify the extent of vascular and tissue damage, potentially leading to better management of their condition.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment options for patients suffering from scleroderma-related complications.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for assessing vascular conditions, suggesting that this approach could yield valuable insights for scleroderma patients.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Feher, Attila — Yale University
- Study coordinator: Feher, Attila
Related research
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Researchers are studying how specific autoantibodies in scleroderma patients relate to cancer timing and risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.