Using advanced imaging to study how cells stick together and behave.
Official title: Monitor single-cell dynamics using optically computed phase microscopy in correlation with fluorescence characterization of intracellular properties
Funded at New Jersey Institute of Technology · NIH-10589414 · Data updated 2026-11-12
This study is working on a new way to take pictures of cells to see how they move and stick together, which could help us understand diseases better and lead to better tests and treatments for patients.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New Jersey Institute of Technology NIH-funded |
| Lab location | 1 site (Newark, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $445,910 |
| NIH project number | 1R15GM148990-01 |
| Project ID | NIH-10589414 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with conditions influenced by cell adhesion, such as certain cancers and cardiovascular diseases.
✕Less likely to help
Patients with conditions unrelated to cell adhesion or those who do not require advanced imaging techniques may not benefit from this research.
What this research studies
This research aims to create a new imaging platform that combines complex phase microscopy and fluorescence microscopy to observe how cells move and interact at a microscopic level. By examining cell adhesion, which is crucial for various diseases, the study seeks to uncover important insights into cell behavior and disease mechanisms. Patients may benefit from improved diagnostic methods and treatments based on a better understanding of cellular dynamics. The research will also explore the development of new biomaterials that can interact with cells in specific ways.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic tools and treatments for diseases related to cell adhesion.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques to study cellular behavior, indicating that this approach could yield valuable insights.
Where this research is happening
-
New Jersey Institute of Technology
Newark, United States Active
Researchers
- Principal investigator: Liu, Xuan — New Jersey Institute of Technology
- Study coordinator: Liu, Xuan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.