NIH-funded research R01 grant

Using advanced imaging to detect bile duct cancer early

Official title: Multispectral imaging of bile duct epithelial morphology for early detection of malignancy

Funded at Beth Israel Deaconess Medical Center · NIH-10944316 · Data updated 2026-11-12

This study is working on a new way to help doctors find bile duct cancer earlier and more accurately during routine check-ups, using a special light technology that makes it easier to spot any early signs of trouble without needing more invasive tests.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBeth Israel Deaconess Medical Center
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 1, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$696,892
NIH project number1R01CA293050-01
Project IDNIH-10944316 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals at risk for bile duct cancer or those undergoing procedures related to bile duct evaluation.

Less likely to help

Patients with no symptoms or known risk factors for bile duct cancer may not benefit from this research.

What this research studies

This research focuses on improving the early detection of bile duct cancer, also known as cholangiocarcinoma, which is often lethal if not caught in time. The team is developing a new diagnostic technology that combines light scattering and diffuse reflectance spectroscopy to identify pre-cancerous and early cancerous changes in the bile duct during routine procedures. By using a specialized fiber optic probe, the goal is to scan the bile duct's internal surface more effectively and quickly, enhancing the accuracy of diagnosis without needing more invasive techniques. This innovative approach aims to provide a reliable method for detecting bile duct malignancies at an earlier stage.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate detection of bile duct cancer, significantly improving patient outcomes.

How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for cancer detection, indicating potential success for this novel approach.

Where this research is happening

  • Beth Israel Deaconess Medical Center
    Boston, United States
    Active

Researchers

  • Principal investigator: Perelman, Lev T — Beth Israel Deaconess Medical Center
  • Study coordinator: Perelman, Lev T

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.