Using advanced imaging techniques to study kidney diseases
Multimodal Imaging Mass Spectrometry and Spatial Omics for the Human Kidney
This study is looking at kidney tissue samples from people with acute kidney injury and chronic kidney disease to find out more about what causes these conditions, with the hope of discovering new ways to improve treatments for kidney problems.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project ID | NIH-10892657 on NIH RePORTER |
What this research studies
This research focuses on utilizing cutting-edge multimodal imaging and spatial omics technologies to analyze kidney biopsies from patients suffering from acute kidney injury and chronic kidney disease. By examining the molecular characteristics of these biopsies, the project aims to uncover the underlying pathways and drivers of kidney disease variability. The study will employ innovative imaging methods and advanced data analysis to identify potential biomarkers that could lead to improved treatment strategies for kidney conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with acute kidney injury or chronic kidney disease who are undergoing kidney biopsy.
Not a fit: Patients with stable kidney function or those not requiring a biopsy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better-targeted therapies and improved outcomes for patients with kidney diseases.
How similar studies have performed: Previous research using similar multimodal imaging approaches has shown promise in understanding complex diseases, indicating potential for success in this novel application.
Where this research is happening
Nashville, UNITED STATES
- Vanderbilt University — Nashville, United States (Active)
Researchers
- Principal investigator: Spraggins, Jeffrey M — Vanderbilt University
- Study coordinator: Spraggins, Jeffrey M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.