Understanding Kidney Disease with Advanced Imaging
Multimodal Imaging Mass Spectrometry and Spatial Omics for the Human Kidney
This project uses advanced imaging and molecular tools to better understand kidney disease in patients with acute kidney injury and chronic kidney disease.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project ID | NIH-11173648 on NIH RePORTER |
What this research studies
We are using special imaging techniques and molecular analysis on kidney tissue samples from patients. Our goal is to create detailed pictures and maps of the kidney at a cellular level, looking at proteins and other molecules. This helps us find the specific changes that cause kidney diseases to progress differently in each person. By understanding these differences, we hope to discover new ways to diagnose and treat kidney conditions more effectively.
Who could benefit from this research
Good fit: This research focuses on patients who have acute kidney injury (AKI) or chronic kidney disease (CKD) and have provided kidney tissue biopsies.
Not a fit: Patients without acute or chronic kidney disease, or those not providing tissue samples, would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to identify specific markers for kidney disease and help develop more personalized treatments for patients.
How similar studies have performed: While the specific combination of advanced imaging and spatial omics is innovative, similar molecular profiling approaches have shown promise in understanding other complex diseases.
Where this research is happening
Nashville, UNITED STATES
- Vanderbilt University — Nashville, United States (Active)
Researchers
- Principal investigator: Spraggins, Jeffrey M — Vanderbilt University
- Study coordinator: Spraggins, Jeffrey M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.