Using advanced imaging techniques to assess retinal health in people with multiple sclerosis
OCT and OCTA image processing for retinal assessment of people with MS
This study is looking to improve how we check the eye health of people with multiple sclerosis by using special imaging techniques, which could help us better understand how changes in the eyes relate to MS and lead to better ways to monitor and treat the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10818611 on NIH RePORTER |
What this research studies
This research focuses on improving the assessment of retinal health in individuals with multiple sclerosis (MS) using advanced imaging techniques called optical coherence tomography (OCT) and OCT angiography (OCTA). By developing new algorithms for analyzing retinal images, the project aims to provide more accurate biomarkers that correlate with MS disease burden and disability. Patients will undergo retinal imaging to help researchers understand the relationship between retinal changes and MS progression, potentially leading to better monitoring and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with multiple sclerosis who are undergoing routine eye examinations.
Not a fit: Patients without a diagnosis of multiple sclerosis or those with unrelated ocular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise monitoring of MS progression and improved treatment outcomes for patients.
How similar studies have performed: Previous research has shown that OCT and OCTA can provide valuable insights into MS, indicating that this approach has potential for success.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Prince, Jerry L — Johns Hopkins University
- Study coordinator: Prince, Jerry L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.