Using advanced 3-D imaging to improve breast cancer risk prediction

Evaluation of novel tomosynthesis density measures in breast cancer risk prediction

NIH-funded research Mayo Clinic Rochester · NIH-11032029

This study is looking at how a special 3-D breast imaging technique can help better predict breast cancer risk by measuring breast density, and it's for women who are having routine screenings to find out if they might be at higher risk for more serious types of breast cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11032029 on NIH RePORTER

What this research studies

This research investigates how digital breast tomosynthesis (DBT), a 3-D imaging technology, can enhance the prediction of breast cancer risk by accurately measuring breast density. By analyzing data from large and diverse cohorts, the study aims to evaluate the effectiveness of DBT volumetric density measures in identifying women at higher risk for invasive and advanced breast cancer. The research will utilize advanced AI algorithms to refine risk models and tailor prevention strategies based on individual characteristics. Participants will undergo routine DBT screenings, with follow-up assessments to track breast cancer outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are women undergoing routine breast cancer screenings who have varying levels of breast density and belong to diverse racial groups.

Not a fit: Patients who do not undergo routine breast cancer screenings or those with conditions that preclude the use of DBT may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate breast cancer risk assessments, enabling personalized screening and prevention strategies for women.

How similar studies have performed: Previous research has shown promising results in using advanced imaging techniques for breast cancer risk assessment, suggesting that this approach may yield significant advancements.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions advanced breast cancerAdvanced Canceradvanced stage breast cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.