NIH-funded research NIH-funded research

Upgrade the genomics lab to faster, more reliable foodborne pathogen sequencing

Official title: Improvement of laboratory capacity for outbreak investigation of foodbornepathogens for FDA VET-LIRN

Funded at Ohio State Department of Agriculture · NIH-11526946 · Data updated 2026-11-12

A state agricultural lab is updating its sequencing machine to quickly and accurately study foodborne germs that affect both animals and people.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOhio State Department of Agriculture
NIH-funded
Lab location1 site (Reynoldsburg, United States)
Project startSeptember 1, 2026
Project endAugust 31, 2027
Funding year2026
Award (this year)$66,400
NIH project number1U18FD008917-01
Project IDNIH-11526946 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable to patients directly; this grant supports laboratory capacity that benefits animal and human health through improved outbreak investigation.

Less likely to help

Direct patient benefit is not the focus; the impact is through enhanced public health response and food safety.

What this research studies

This project replaces an aging sequencer with a newer Illumina MiSeq i100 at ADDL to improve whole genome sequencing of foodborne pathogens. The upgraded system will support AMR monitoring, outbreak investigations, and One Health surveillance under Vet-LIRN, with validated workflows and data sharing to FDA and public health partners. The work includes instrument installation, method verification, and staff training within the lab's quality management system to ensure reliable results. The aim is to maintain uninterrupted sequencing capacity during surges from outbreaks or contamination events, thereby strengthening national food safety readiness.

Why it matters

Potential benefit: If successful, clinicians and public health teams could receive faster, higher-quality genomic data to guide outbreak response and prevention efforts.

How similar studies have gone: Upgrading sequencing capacity has shown improvements in turnaround time and data quality in similar public health laboratory settings.

Where this research is happening

  • Ohio State Department of Agriculture
    Reynoldsburg, United States
    Active

Researchers

  • Principal investigator: Prarat, Melanie — Ohio State Department of Agriculture
  • Study coordinator: Prarat, Melanie

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.