University of Wisconsin Prostate Cancer Program
University of Wisconsin Prostate SPORE
This program brings scientists and prostate cancer doctors together to develop new tests and treatments for men with advanced or treatment-resistant prostate cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11184182 on NIH RePORTER |
What this research studies
I would join a coordinated effort where lab scientists and clinical teams work together to tackle why some prostate cancers stop responding to treatment. The program focuses on three areas: how the tumor environment drives metastasis in high-risk disease, using hormone-lowering therapy to help immunotherapy work better, and targeting resistant lesions in metastatic castration-resistant prostate cancer. Shared cores will provide pathology, imaging, and data support while training programs bring new researchers into the work. The goal is to move promising lab findings into real patient care to improve survival and quality of life.
Who could benefit from this research
Good fit: Ideal candidates are men with high-risk, advanced, or treatment‑resistant prostate cancer (including metastatic castration‑resistant prostate cancer) who can receive care at or near the study sites.
Not a fit: Patients with early-stage, low-risk prostate cancer or those unable to travel to participating centers are less likely to directly benefit from these projects.
Why it matters
Potential benefit: If successful, this program could produce new ways to overcome treatment resistance and improve survival and quality of life for men with advanced prostate cancer.
How similar studies have performed: Components like combining androgen‑lowering therapy with immunotherapy and treating resistant lesions have shown promise in prior trials, though integrating these approaches in a coordinated SPORE program is still being developed.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Jarrard, David F. — University of Wisconsin-Madison
- Study coordinator: Jarrard, David F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.