Understanding why patients don't use statins for heart disease prevention
Official title: Adherence Determinants in the Health Electronic Record Evaluation of Statins (ADHERES)
Funded at Stanford University · NIH-10995339 · Data updated 2026-11-12
This study is looking into why some people, especially from diverse backgrounds, aren't using statins, which are important for preventing heart disease, and it aims to find ways to help more patients stick to their medication.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | December 15, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $616,165 |
| NIH project number | 5R01HL168188-02 |
| Project ID | NIH-10995339 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals from historically marginalized racial and ethnic groups, women, and older adults who are at risk for atherosclerotic cardiovascular disease.
✕Less likely to help
Patients who are already adherent to statin therapy or those without risk factors for atherosclerotic cardiovascular disease may not benefit from this research.
What this research studies
This research investigates the reasons behind the low usage of statins, which are crucial for preventing atherosclerotic cardiovascular disease (ASCVD), particularly among diverse populations. By analyzing electronic health record (EHR) data and conducting focus groups, the study aims to identify barriers to statin adherence, especially in historically marginalized groups. The research will explore both structured and unstructured data to gain a comprehensive understanding of patient, clinician, and health system factors affecting statin use. Ultimately, the goal is to develop strategies to improve adherence and reduce health disparities in cardiovascular care.
Why it matters
Potential benefit: If successful, this research could lead to improved access and adherence to statin therapy, significantly reducing the risk of heart disease in vulnerable populations.
How similar studies have gone: Previous research has shown that addressing adherence barriers through targeted interventions can improve medication use in similar populations, indicating potential for success in this approach.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Rodriguez, Fatima — Stanford University
- Study coordinator: Rodriguez, Fatima
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.