Understanding the roles of glycoproteins in cell communication and disease
Characterizing extracellular glycoproteins and unraveling their functions
This study is looking at special proteins on our cells that help them communicate and respond to changes, with the hope of finding new ways to detect diseases like cancer early and understand how they work, so we can develop better treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11011841 on NIH RePORTER |
What this research studies
This research investigates the functions of glycoproteins found on cell surfaces and in bodily fluids, which are crucial for cell communication and responses to environmental changes. By characterizing these glycoproteins, the research aims to uncover their roles in diseases like cancer and develop methods for early disease detection using non-invasive biomarkers. The study employs advanced techniques to separate and analyze these proteins, despite the challenges posed by their low abundance and complexity in biological samples. The ultimate goal is to enhance our understanding of disease mechanisms and identify potential drug targets.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions related to cancer or other diseases influenced by glycoprotein interactions.
Not a fit: Patients with non-cancerous conditions unrelated to glycoprotein functions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection of diseases and the development of targeted therapies.
How similar studies have performed: Previous research has shown promise in using glycoproteins as biomarkers and drug targets, indicating a potential for success in this area.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Wu, Ronghu — Georgia Institute of Technology
- Study coordinator: Wu, Ronghu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.