Understanding the long-term effects of neonatal seizures on child development

Neonatal Seizure Registry Developmental Functional EValuation (NSR-DEV)

NIH-funded research University of California, San Francisco · NIH-10550229

This study is looking at how seizures in newborns, caused by brain injury, can impact a child's growth and development over time, and it’s for parents of kids who have had these seizures to help understand what factors might affect their child's future.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10550229 on NIH RePORTER

What this research studies

This research investigates how neonatal seizures, which occur due to brain injury, affect the long-term development of children. By following a cohort of over 300 children who experienced these seizures, the study aims to identify risk factors for developmental disabilities and how parental well-being influences these outcomes. Parents will provide annual reports on their child's development, and children will undergo standardized IQ testing at age 5. The study utilizes clinical data, EEG, and MRI measures to create predictive models for developmental outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 2-7 years who have experienced neonatal seizures.

Not a fit: Patients who have not experienced neonatal seizures or are older than 7 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for children at risk of developmental disabilities due to neonatal seizures.

How similar studies have performed: Similar research has shown promise in understanding the long-term effects of neonatal conditions on child development, making this approach both relevant and potentially impactful.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric DiseasePsychiatric Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.