Understanding the genetics of avoidant/restrictive food intake disorder

Genetic Architecture of Avoidant/Restrictive Food Intake Disorder

['FUNDING_OTHER'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-10684064

This study is looking at the genes that might play a role in avoidant/restrictive food intake disorder (ARFID) by gathering information from 5,000 people with ARFID and 1,000 children without the condition, to help us understand what makes ARFID different from other eating disorders and improve treatment options.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIV OF NORTH CAROLINA CHAPEL HILL (nih funded)
Locations1 site (CHAPEL HILL, UNITED STATES)
Trial IDNIH-10684064 on ClinicalTrials.gov

What this research studies

This research investigates the genetic factors associated with avoidant/restrictive food intake disorder (ARFID), a condition characterized by food avoidance due to various reasons such as phobia, sensory sensitivity, or lack of interest. The study aims to collect genetic data from 5,000 individuals with ARFID and 1,000 child controls to identify genetic markers linked to this disorder. By leveraging existing resources from the Eating Disorders Genetic Initiative, the research seeks to uncover both shared and unique genetic factors that differentiate ARFID from other eating disorders. This could lead to a better understanding of the biological underpinnings of ARFID and improve treatment approaches.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with avoidant/restrictive food intake disorder, particularly those aged 21 and older.

Not a fit: Patients with eating disorders other than ARFID, such as anorexia nervosa or bulimia nervosa, may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments and interventions for individuals suffering from ARFID.

How similar studies have performed: Other genetic studies on eating disorders have shown promise, indicating that this approach could yield valuable insights into ARFID as well.

Where this research is happening

CHAPEL HILL, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Mental disorders, Mental health disorders, Psychiatric Disease, Psychiatric Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.