Understanding the genetics behind complex human traits and diseases
Official title: A Resource for the Genetic Dissection of Complex Traits
Funded at University of Kansas Lawrence · NIH-10995285 · Data updated 2026-11-12
This study is looking at how our genes affect health and diseases by comparing different people's DNA, which could help doctors find better ways to diagnose and treat conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Lawrence NIH-funded |
| Lab location | 1 site (Lawrence, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $479,303 |
| NIH project number | 5R01OD034064-03 |
| Project ID | NIH-10995285 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with complex genetic conditions or those interested in understanding the genetic basis of their health traits.
✕Less likely to help
Patients with purely environmental or non-genetic conditions may not benefit from this research.
What this research studies
This research investigates the genetic factors that contribute to complex human diseases and traits by analyzing population variations. It utilizes genomewide association studies (GWAS) to identify genes linked to health variations, focusing on both common and rare genetic variants. By studying model organisms, the research aims to uncover the molecular and cellular processes that underlie these traits, potentially leading to better diagnostics and treatments for patients. The approach combines traditional genetic analysis with innovative methods to provide a more comprehensive understanding of genetic influences on health.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostics and targeted therapies for complex diseases.
How similar studies have gone: Previous research using genomewide association studies has shown significant success in linking genetic variants to various health conditions, indicating a promising approach.
Where this research is happening
-
University of Kansas Lawrence
Lawrence, United States Active
Researchers
- Principal investigator: Macdonald, Stuart John — University of Kansas Lawrence
- Study coordinator: Macdonald, Stuart John
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.