Sponsor or institution
Clinical trials and research at University of Kansas Lawrence
As of November 12, 2026, Find a Trial lists 120 NIH-funded research projects at this institution, with $48.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 120NIH research projects
NIH-funded research (newest 40 of 120)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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KC Youth Violence Prevention Center: A comprehensive plan to reduce youth violence
A program in Kansas City aims to reduce youth violence and deaths by applying a coordinated, community-focused approach.
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Gene regulation and the genetic basis of complex traits (how our genes influence survival and trait differences)
Researchers are studying how genetic differences that affect gene regulation contribute to when and how people survive and reproduce, especially in natural populations.
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Finding new treatments and understanding how congenital glycosylation disorders work
A research project aims to uncover how certain congenital glycosylation disorders develop and identify existing drugs that could help treat DPAGT1-CDG.
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How ADP-ribosylation controls our antiviral defenses
Researchers are studying a cellular modification called ADP-ribosylation and how it helps the body fight viruses, with a focus on how coronaviruses interact with this process.
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Chemoenzymatic synthesis to make biologically active molecules using enzyme libraries
A scientist team will develop enzyme-based methods to make complex drug-like molecules that could help fight cancer and other diseases.
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DNA breaks and repair in opioid addiction
This project looks at how DNA damage and repair in brain cells may influence opioid addiction and relapse in people and animal models.
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Technology tools for better mass spectrometry to study biology
A national research project is developing new noninvasive sampling methods and improved data analysis tools for mass spectrometry to help understand biology and disease, including in children.
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Peptides to block and deliver drugs in a key bacterial pump to fight antibiotic resistance
A research project at a university aims to design peptides that plug the TolC bacterial efflux pump, making antibiotics work better against resistant infections.
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CRISPR screen reveals how hosts respond to DNA viruses in fruit flies
A researcher is using gene editing in fruit flies to uncover which host genes influence how DNA viruses infect cells, with potential implications for human infections.
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FXS: Late Adolescence and Early Adulthood
A long-term study following children with fragile X syndrome and their mothers as they move from teens into early adulthood, looking at how daily life and family factors affect outcomes.
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Protective and Risk Factors for Cognitive Function in the Menopause Transition
This grant explores how lifestyle, sleep, and cardiometabolic factors affect thinking and memory during menopause to help women maintain cognitive health.
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Rural women's health: how demographics and migration affect health and longevity
This grant looks at how changes in who lives in rural areas influence health and lifespan for women.
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Telemedicine access for rural families and caregivers
A big-data study to see how expanding telemedicine in rural areas could affect the health and daily lives of caregivers with kids up to 11 years old.
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Understanding how CA125 detection works in ovarian cancer
A research team is studying why the CA125 blood test sometimes misses parts of the ovarian cancer signal and how this could improve how doctors monitor the disease.
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Estrogen and brain cholesterol during myelin damage and repair
Women with neurological diseases may have worse symptoms after menopause, so this study looks at how estrogen influences brain fats and myelin healing in a way that could help future therapies.
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Biomedical Data Sets and Services Core for biomedical and behavioral research
A University of Kansas program is creating a central data hub to connect medical, environmental, health records, and survey data to help researchers study how biology and behavior influence health.
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Administrative and Professional Development Core for Women’s Health Data Science
A core grant to grow experts in data-driven women’s health research and to build cross-disciplinary teams at the University of Kansas.
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Leveraging Big Data to Improve Women’s Health (BD-WH) at KU
A big-data grant from NIH aims to help women’s health by using data science to understand and prevent chronic diseases that affect women and the general population.
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Adaptive Functional Fitness for Adults with Mobility Disabilities
A community-based fitness program tailored for adults with mobility challenges is being tested to see if it improves daily function and keeps people moving over 18 months.
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New 400 MHz NMR Spectrometer for KU’s Biomedical Research Core
This grant funds a state-of-the-art 400 MHz NMR spectrometer to support KU’s 15 research groups, including NIH-funded teams, by providing a modern tool for chemical biology and related bioscience work.
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Infant Learning and How It Predicts Thinking Skills
This project studies how very young children learn from their actions and how those learning patterns relate to later thinking and language skills.
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Micro- and Nanofluidic Tools to Understand Biology and Personalize Care
A center project is developing tiny fluidic tools that help generate multi-omics data to support precision medicine and train researchers in new bioengineering techniques.
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Modular fluidic systems to analyze tiny patient samples
A research project aims to build compact, easy-to-use fluidic devices to run complex liquid biopsy tests on very small patient samples, with a focus on cancer, stroke, and bacterial infections.
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Advancing nanopore sensors for faster, cheaper molecule identification
A patient-friendly project to help develop a fast, low-cost device that can identify single molecules without labels, which could speed diagnoses and personalized treatment in the future.
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Single-molecule processing to detect DNA, RNA, and proteins without amplification
A research center grant aims to develop methods to detect and identify individual DNA, RNA, and protein molecules and their modifications without PCR, which could improve disease diagnostics.
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Administrative Core for a Center that advances precision medicine using liquid biopsy tools
This NIH grant funds an Administrative Core to support a center that develops and refines liquid biopsy technologies to guide personalized care.
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CBM2 Center for Precision Medicine: modular systems to transform liquid biopsy biomarkers
A national lab network is building modular, multi-omics tech to better analyze liquid biopsy markers for personalized medicine.
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Modeling how macromolecules interact inside living cells
A researchers team will use advanced computer models to simulate how big proteins and other molecules interact inside cells, aiming to understand the energy landscapes and dynamics of these interactions.
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Gut bacteria chemicals that help protect against cholera
This project looks at chemicals made by gut bacteria to find ways to prevent or reduce cholera infections in people.
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Oral approach to strengthen gut defenses against infection and inflammation
An oral vaccine helper designed to activate gut immune cells to give people stronger protection from gastrointestinal infections.
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Targeting PTPN22 to strengthen antiviral defenses
The team is developing drugs that target the PTPN22 protein to strengthen antiviral immunity in people who struggle to clear persistent viral infections.
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Gene regulation and how variations influence complex traits
Scientists are studying how tiny genetic differences affect how traits develop and how this plays out in human health, especially in natural populations.
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New ways to make non-standard amino acid peptides for GPCR drugs
Researchers are developing new chemical methods to create peptide drugs with non-standard amino acids to better target GPCRs in people with HIV-related conditions.
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Adaptive peer-supported play to boost social skills for preschoolers with autism who are minimally verbal
A research study is testing different friendly, peer-led play strategies to help 3–6 year-olds with autism improve how they talk and interact with peers.
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Better ways to get medicines into the brain
This project develops peptide-based methods to temporarily let medicines into the brain for people with Alzheimer’s disease and other brain injuries.
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Modifying harmful oral microbes with smart peptides guided by machine learning
A study aims to use machine learning to guide the design of targeted antimicrobial peptides that reshape the oral microbiome to help treat periodontitis in teens and adults.
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How the brain enzyme gamma‑secretase makes amyloid in Alzheimer's
This project explains how the gamma‑secretase enzyme produces different forms of amyloid protein that can drive Alzheimer's disease in people.
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Brain circuits behind partner-seeking after losing a loved one
This project looks at brain circuits in animal models to learn why some people have prolonged partner-seeking and emotional pain after losing a loved one.
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How cells change their metabolism when stressed
This project looks at how human cells rewire their metabolism under stress to help people with chronic diseases in the future.
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Healthy Eating and Self‑Esteem App for College Students with Binge Eating
A guided cognitive‑behavioral mobile program for college students with binge eating that aims to reduce binge episodes and improve body image and wellbeing.
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