Understanding the genetic links between alcohol use disorder and chronic pain
Official title: Genetic Architecture of the Comorbidity of Alcohol Use Disorder and Chronic Pain
Funded at George Washington University · NIH-10741891 · Data updated 2026-11-12
This study is looking at how our genes might link alcohol use problems and chronic pain, especially in older adults, to help people who struggle with these issues understand their conditions better and find better treatments.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | George Washington University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | August 2, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $424,194 |
| NIH project number | 1R21AA030360-01A1 |
| Project ID | NIH-10741891 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing both alcohol use disorder and chronic pain.
✕Less likely to help
Patients who do not have a history of alcohol use disorder or chronic pain may not benefit from this research.
What this research studies
This research investigates how genetic factors may contribute to the co-occurrence of alcohol use disorder (AUD) and chronic pain (CP), which often affect older adults. By analyzing large-scale genetic data, the study aims to identify shared genetic influences and understand the relationship between these two conditions. Patients with a history of heavy drinking or chronic pain may find insights into their conditions through this research, as it seeks to uncover the underlying genetic mechanisms. The study employs advanced statistical methods to explore these connections, potentially leading to more effective treatments.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients suffering from both alcohol use disorder and chronic pain.
How similar studies have gone: Previous research has shown promising results in understanding the genetic basis of alcohol use disorder and chronic pain, suggesting that this approach may yield valuable insights.
Where this research is happening
-
George Washington University
Washington, United States Active
Researchers
- Principal investigator: Yeung, Ellen Wanheung — George Washington University
- Study coordinator: Yeung, Ellen Wanheung
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.