Understanding the genetic links between alcohol use disorder and chronic pain

Genetic Architecture of the Comorbidity of Alcohol Use Disorder and Chronic Pain

['FUNDING_R21'] · GEORGE WASHINGTON UNIVERSITY · NIH-10741891

This study is looking at how our genes might link alcohol use problems and chronic pain, especially in older adults, to help people who struggle with these issues understand their conditions better and find better treatments.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorGEORGE WASHINGTON UNIVERSITY (nih funded)
Locations1 site (WASHINGTON, UNITED STATES)
Trial IDNIH-10741891 on ClinicalTrials.gov

What this research studies

This research investigates how genetic factors may contribute to the co-occurrence of alcohol use disorder (AUD) and chronic pain (CP), which often affect older adults. By analyzing large-scale genetic data, the study aims to identify shared genetic influences and understand the relationship between these two conditions. Patients with a history of heavy drinking or chronic pain may find insights into their conditions through this research, as it seeks to uncover the underlying genetic mechanisms. The study employs advanced statistical methods to explore these connections, potentially leading to more effective treatments.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults experiencing both alcohol use disorder and chronic pain.

Not a fit: Patients who do not have a history of alcohol use disorder or chronic pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for patients suffering from both alcohol use disorder and chronic pain.

How similar studies have performed: Previous research has shown promising results in understanding the genetic basis of alcohol use disorder and chronic pain, suggesting that this approach may yield valuable insights.

Where this research is happening

WASHINGTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: ethanol use disorder, alcohol use disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.