Understanding the genetic factors in type 1 diabetes
Characterizing Immunogenetics in Type 1 Diabetes
This study is looking at how certain genes might affect the start and progression of type 1 diabetes, with the hope of finding new ways to improve screening, diagnosis, and treatment for people living with this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11046646 on NIH RePORTER |
What this research studies
This research investigates the genetic mechanisms that contribute to the onset and progression of type 1 diabetes mellitus (T1DM). By focusing on specific genetic segments within the HLA/KIR/FcGR/IGHG genes, the study aims to identify novel regulatory elements that influence disease progression. Utilizing advanced genetic sequencing techniques, the researchers will analyze genetic variations that may not be captured by traditional methods. The ultimate goal is to develop better screening, diagnostic, preventive, and treatment strategies for T1DM.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of type 1 diabetes or those who have shown early signs of autoimmune activity related to the disease.
Not a fit: Patients who are already diagnosed with advanced type 1 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for preventing or delaying the onset of type 1 diabetes in at-risk individuals.
How similar studies have performed: Previous studies have shown promise in identifying genetic markers associated with type 1 diabetes, suggesting that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Zhao, Lue Ping — Fred Hutchinson Cancer Center
- Study coordinator: Zhao, Lue Ping
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.