Understanding the Genetic Causes of Cerebral Palsy
Characterizing the spectrum of genomic and phenotypic variation in cerebral palsy
['FUNDING_R01'] · GEISINGER CLINIC · NIH-11139414
This project aims to discover the genetic reasons why some people develop cerebral palsy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEISINGER CLINIC (nih funded) |
| Locations | 1 site (DANVILLE, UNITED STATES) |
| Trial ID | NIH-11139414 on ClinicalTrials.gov |
What this research studies
We want to understand all the genetic factors that contribute to cerebral palsy, including both rare and common genetic changes. To do this, we are looking at genetic information from two groups: children with cerebral palsy who had genetic testing, and adults with cerebral palsy from a large health study. By comparing their genetic information with their health records and brain imaging, we hope to find specific genetic causes for their condition. This will help us better understand why cerebral palsy happens and how it affects individuals.
Who could benefit from this research
Good fit: This research uses existing genetic and health data from individuals with cerebral palsy, including both children and adults.
Not a fit: Patients not diagnosed with cerebral palsy would not directly benefit from the findings of this specific genetic research.
Why it matters
Potential benefit: If successful, this work could lead to a better understanding of cerebral palsy's causes, potentially improving diagnosis and guiding future treatment strategies.
How similar studies have performed: Other studies have successfully identified rare genomic variants as causes for similar developmental brain disorders, suggesting a promising approach for cerebral palsy.
Where this research is happening
DANVILLE, UNITED STATES
- GEISINGER CLINIC — DANVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MYERS, SCOTT — GEISINGER CLINIC
- Study coordinator: MYERS, SCOTT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autistic Disorder, Brain Diseases, Brain Disorders, Candidate Disease Gene