Understanding the effects of small brain injuries on blood flow and neural function
Longitudinal multimodal mapping to decipher the neurovascular impact of microinfarcts
This study is looking at how small brain injuries, called microinfarcts, change blood flow and brain activity over time in mice, with the goal of understanding their long-term effects so we can help people who might have similar issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rice University NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10556319 on NIH RePORTER |
What this research studies
This research investigates how tiny brain injuries, known as microinfarcts, affect blood flow and brain function over time. Using a mouse model, the study aims to track changes in both blood circulation and neural activity in response to these microinfarcts. By employing advanced imaging techniques, researchers hope to uncover the long-term impacts of these injuries, which often go unnoticed but can lead to significant neurological issues. The findings could help in developing targeted interventions for patients with similar conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of cerebrovascular issues or neurological dysfunctions, particularly those who may have experienced unnoticed small brain injuries.
Not a fit: Patients without any history of cerebrovascular disorders or neurological impairments are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for patients suffering from neurological dysfunctions related to microinfarcts.
How similar studies have performed: While the investigation of microinfarcts is a relatively novel approach, previous studies have shown promising results in understanding larger infarcts and their impacts on brain function.
Where this research is happening
Houston, United States
- Rice University — Houston, United States (Active)
Researchers
- Principal investigator: Luan, Lan — Rice University
- Study coordinator: Luan, Lan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.