Understanding the early stages of autoimmune diseases

Core 1

NIH-funded research University of Colorado Denver · NIH-10908349

This study is looking at the early signs of rheumatic and autoimmune diseases to find ways to prevent them, focusing on how inflammation and the immune system change over time, so we can help people get better diagnoses and treatments.

Quick facts

Grant typeP30 center grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-10908349 on NIH RePORTER

What this research studies

This research investigates the early stages of rheumatic and autoimmune diseases, focusing on identifying a 'pre-disease' state that can lead to prevention strategies. It aims to understand the mechanisms that trigger these diseases, particularly the role of chronic inflammation and changes in the immune system. By studying various stages of disease development and integrating data from different body sites, the research seeks to improve diagnosis and treatment options for affected individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at risk for autoimmune diseases, such as those with positive predictive biomarkers or a family history of these conditions.

Not a fit: Patients who are already diagnosed with advanced autoimmune diseases may not benefit directly from this research.

Why it matters

Potential benefit: If successful, this research could lead to new prevention strategies for autoimmune diseases, potentially reducing the incidence and severity of these conditions.

How similar studies have performed: Previous research has shown promise in identifying pre-disease states in autoimmune diseases, suggesting that this approach could lead to significant advancements in prevention.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autoimmune DiseasesBrittle Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.