Understanding the causes of enlarged prostate in mice
Official title: Validating Mouse Models of Prostatic Hyperplasia
Funded at Endeavor Health Clinical Operations · NIH-10951924 · Data updated 2026-11-12
This study is looking at benign prostatic hyperplasia (BPH), a common issue that causes urinary problems in men, by comparing mouse models to human tissue to find better ways to treat it, which could lead to improved therapies for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Endeavor Health Clinical Operations NIH-funded |
| Lab location | 1 site (Evanston, United States) |
| Project start | August 1, 2024 |
| Project end | May 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $387,016 |
| NIH project number | 1P20DK140417-01 |
| Project ID | NIH-10951924 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men experiencing symptoms of benign prostatic hyperplasia or those at risk for developing the condition.
✕Less likely to help
Patients with prostate cancer or other unrelated urinary conditions may not benefit from this research.
What this research studies
This research investigates benign prostatic hyperplasia (BPH), a common condition that leads to urinary issues in men. By using advanced techniques like single-cell RNA sequencing, the study aims to compare mouse models of BPH with human tissue to better understand the disease's underlying mechanisms. The goal is to identify specific mouse models that accurately reflect human BPH, which could help in developing targeted treatments. Patients may benefit from improved therapies derived from a better understanding of BPH.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for benign prostatic hyperplasia, improving quality of life for patients.
How similar studies have gone: Previous research has shown promise in using mouse models to study human diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
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Endeavor Health Clinical Operations
Evanston, United States Active
Researchers
- Principal investigator: Vickman, Renee E. — Endeavor Health Clinical Operations
- Study coordinator: Vickman, Renee E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.