Understanding T cell regulation in infections and tumors
Regulatory genomics of T cells in mouse and human
['FUNDING_OTHER'] · PRINCETON UNIVERSITY · NIH-11124665
This project explores how immune cells called T cells work to protect us from infections and tumors, aiming to find new ways to boost our body's defenses.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PRINCETON UNIVERSITY (nih funded) |
| Locations | 1 site (Princeton, UNITED STATES) |
| Trial ID | NIH-11124665 on ClinicalTrials.gov |
What this research studies
Our immune system relies on T cells to fight off bacteria, viruses, and even cancer. This project uses advanced genomic tools to understand exactly how these T cells become active and specialize to perform their protective roles. We are looking at how T cells respond to different triggers, comparing these processes in both mouse models and human cells. The goal is to build a detailed picture of T cell behavior, which could lead to new strategies for treating various diseases.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation but aims to benefit individuals susceptible to or suffering from bacterial infections, viral diseases, or cancer.
Not a fit: Patients seeking immediate new treatments or direct clinical intervention would not find direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to new ways to enhance our immune system's ability to fight off bacterial infections, viral diseases, and tumors.
How similar studies have performed: While the overall approach of studying T cell genomics is established, this project aims to develop innovative experimental and computational methods for unprecedented resolution and comparative analysis.
Where this research is happening
Princeton, UNITED STATES
- PRINCETON UNIVERSITY — Princeton, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PRITYKIN, YURY — PRINCETON UNIVERSITY
- Study coordinator: PRITYKIN, YURY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bacterial Infections