NIH-funded research R01 grant

Understanding social behavior and its dysfunction in primates

Official title: A formal group theory-based model in primates for studying interactive social behavior and its dysfunction

Funded at Massachusetts General Hospital · NIH-11014980 · Data updated 2026-11-12

This study looks at how primates interact with each other and what happens when those interactions go wrong, which could help us understand social challenges in people with autism.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startMarch 1, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$408,299
NIH project number5R01MH131664-03
Project IDNIH-11014980 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research would include individuals with autism spectrum disorder or related social behavior dysfunctions.

Less likely to help

Patients with conditions unrelated to social behavior dysfunction may not receive any benefit from this research.

What this research studies

This research investigates the neural basis of interactive social behavior in primates, focusing on how these behaviors can become dysfunctional. By utilizing a formal group theory-based model, the study aims to analyze real-time interactions between primates and identify the neuronal components that encode these behaviors. The approach combines advanced techniques such as multi-site neuronal recordings and neuromodulation to explore the dynamics of social interactions over different time scales. This research could provide insights into conditions like autism spectrum disorder, where social behavior is significantly impacted.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of social behavior dysfunctions, potentially informing treatments for conditions like autism spectrum disorder.

How similar studies have gone: While there has been significant research on solitary behaviors in animal models, this approach to studying interactive social behavior in primates is relatively novel and has not been extensively tested.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Williams, Ziv — Massachusetts General Hospital
  • Study coordinator: Williams, Ziv

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.