Understanding side effects of new cancer treatments using patient feedback

Use of Patient-Reported Outcomes in Understanding Symptomatic Adverse Events in Early-Phase Trials of Combination Treatments that Include Immune Checkpoint Inhibitors and Targeted Therapy

NIH-funded research University of Tx Md Anderson Can Ctr · NIH-10989909

This study is looking to hear from cancer patients about the side effects they experience while receiving combination treatments that include immune checkpoint inhibitors, so we can better understand and manage any unique challenges that come with these therapies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Tx Md Anderson Can Ctr NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10989909 on NIH RePORTER

What this research studies

This research focuses on gathering information from patients about the side effects they experience while undergoing combination cancer treatments that include immune checkpoint inhibitors. By utilizing patient-reported outcomes, the study aims to identify and track immune-related adverse events (irAEs) associated with these therapies. The researchers will analyze data from early-phase clinical trials at a leading cancer center to better understand the safety profiles of these innovative treatments. This approach will help in managing and mitigating the unique toxicities that may arise from these combination therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with advanced cancer who are receiving combination therapies that include immune checkpoint inhibitors.

Not a fit: Patients who are not undergoing combination cancer therapies or those with early-stage cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved management of side effects for patients undergoing advanced cancer treatments.

How similar studies have performed: Previous research has shown promise in using patient-reported outcomes to assess treatment side effects, indicating that this approach could yield valuable insights.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced CancerAnti-Cancer Agentsanti-cancer drug
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.