Understanding side effects in melanoma patients treated with immune therapy
Immune-Related Adverse Events in Melanoma Patients Receiving Adjuvant Immune Checkpoint Inhibitor Therapy
This study is looking at the side effects that melanoma patients might experience while getting treatment with immune checkpoint inhibitors, to better understand how these treatments can help them live longer but may also cause some uncomfortable issues, and it’s for anyone who wants to know more about the long-term effects of this therapy on their health and quality of life.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10893992 on NIH RePORTER |
What this research studies
This research investigates the side effects experienced by melanoma patients receiving immune checkpoint inhibitors (ICIs) as part of their treatment. It aims to understand how these therapies, while improving survival rates, can also lead to inflammatory responses and autoimmune issues that affect patients' quality of life. By following a group of 240 melanoma patients over two years, the study will assess the incidence and severity of these immune-related adverse events (irAEs) and explore their correlation with inflammation markers in the body. The goal is to provide a clearer picture of the long-term effects of ICI therapy on patients' health and well-being.
Who could benefit from this research
Good fit: Ideal candidates for this research are melanoma patients who are starting adjuvant immune checkpoint inhibitor therapy.
Not a fit: Patients who are not receiving immune checkpoint inhibitors or those with other types of cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management of side effects for melanoma patients undergoing immune therapy, enhancing their overall quality of life.
How similar studies have performed: Previous research has shown that understanding the side effects of immune therapies can lead to better patient care, indicating that this approach has potential for success.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Hassan, Noha Abdelwahab Hassan Ali — University of Tx Md Anderson Can Ctr
- Study coordinator: Hassan, Noha Abdelwahab Hassan Ali
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.