Understanding shared genetic factors in various mental health disorders
Comprehensive analysis of genetic pleiotropy in eleven neuropsychiatric disorders
['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10734054
This study is looking at the genes behind eleven mental health conditions to help improve how we prevent, diagnose, and treat these disorders, so that people can get better care based on their unique genetic makeup.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10734054 on ClinicalTrials.gov |
What this research studies
This research investigates the genetic underpinnings of eleven neuropsychiatric disorders to enhance prevention, diagnosis, and treatment options. By analyzing genetic data from over a million individuals, the study aims to identify common genetic risk factors that span across different psychiatric conditions. The researchers will focus on how these genetic factors influence brain development and function, potentially leading to new insights into mental health disorders. Patients may benefit from improved understanding and targeted therapies based on genetic findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with any of the eleven neuropsychiatric disorders being studied.
Not a fit: Patients with mental health conditions not included in the eleven disorders under investigation may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention and treatment strategies for a range of mental health disorders.
How similar studies have performed: Previous large-scale genomic studies have shown success in identifying shared genetic risks across psychiatric disorders, suggesting this approach may yield valuable insights.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, PHIL H. — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: LEE, PHIL H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Anxiety Disorders, Mental health disorders, Psychiatric Disease, Psychiatric Disorder, psychological disorder