NIH-funded research NIH-funded research

Understanding repetitive negative thinking after trauma to help veterans

Official title: Establishing a multidimensional neurocognitive framework for repetitive negative thinking after traumatic stress

Funded at VA San Diego Healthcare System · NIH-11404232 · Data updated 2026-11-12

A VA-led project will study how intrusive thoughts, rumination, and worry unfold in daily life after trauma and how brain activity relates to these moments.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA San Diego Healthcare System
NIH-funded
Lab location1 site (San Diego, United States)
Project startOctober 1, 2026
Project endSeptember 30, 2030
Funding year2026
NIH project number1I01RD002519-01
Project IDNIH-11404232 on NIH RePORTER

Who could benefit from this research

Could help

Veterans with trauma exposure who experience repetitive negative thinking such as intrusive memories, rumination, or worry.

Less likely to help

Patients without significant RNT or trauma exposure may not benefit from this research.

What this research studies

This project focuses on veterans who have experienced trauma and experience repetitive negative thinking (RNT). Researchers will combine real-world mobile assessments of thinking and mood with brain imaging to uncover when RNT tends to flare and what brain patterns accompany it. By studying RNT across different intrusive thoughts and biobehavioral signals, the study aims to identify practical targets for intervention that could be used in daily life. The work plans to link daily symptoms with brain function to guide future personalized treatments.

Why it matters

Potential benefit: If successful, the findings could lead to targeted interventions that reduce daily distress and improve recovery for veterans with PTSD and related conditions.

How similar studies have gone: Previous studies have shown that linking brain activity with real-world symptoms can reveal actionable targets for interventions.

Where this research is happening

  • VA San Diego Healthcare System
    San Diego, United States
    Active

Researchers

  • Principal investigator: Bomyea, Jessica — VA San Diego Healthcare System
  • Study coordinator: Bomyea, Jessica

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.