Understanding protein levels to predict heart disease risk
Proteomics of Cardiovascular Risk: The Multiethnic Study of Atherosclerosis
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10834027
This study is looking at how certain proteins in your blood might help predict your risk of heart disease and heart failure, and it's for people who currently don't have any heart problems.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10834027 on ClinicalTrials.gov |
What this research studies
This research investigates how protein levels in the blood can serve as biomarkers to predict the risk of atherosclerotic cardiovascular disease (ASCVD) and heart failure (HF). By analyzing a diverse group of individuals who are free of cardiovascular disease, the study aims to identify novel risk factors and biological pathways associated with these conditions. Utilizing advanced proteomic technology, the researchers will examine nearly 5,000 proteins in small blood samples to enhance risk prediction and guide future therapies. The findings could lead to better prevention strategies for heart disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are free of cardiovascular disease and are part of a racially diverse population.
Not a fit: Patients with existing cardiovascular disease or those who do not meet the study's demographic criteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for predicting and preventing heart disease, ultimately reducing mortality rates.
How similar studies have performed: Previous research has shown promise in using proteomic approaches to identify biomarkers for cardiovascular diseases, indicating that this method has potential for success.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GANZ, PETER — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: GANZ, PETER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease, atherosclerotic disease, atherosclerotic vascular disease, cardiovascular disorder, Cardiovascular Diseases