Understanding pancreatic function changes before type 1 diabetes develops
Natural History and Mechanisms of Exocrine Pancreatic Dysfunction in Pre-Type 1 Diabetes
['FUNDING_OTHER'] · UNIVERSITY OF FLORIDA · NIH-10989971
This study is looking at how the pancreas works in people who might develop type 1 diabetes, especially those who have family members with the condition, to find early signs of pancreatic problems that could help catch diabetes sooner.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10989971 on ClinicalTrials.gov |
What this research studies
This research investigates how the exocrine function of the pancreas changes in individuals who are at risk of developing type 1 diabetes (T1D). It aims to identify early biomarkers that indicate pancreatic dysfunction before the onset of diabetes. By measuring specific markers in stool and serum, the study will track changes in pancreatic size and function over time in first-degree relatives of T1D patients. This could help in understanding the natural history of T1D and improve early detection methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are first-degree relatives of individuals with type 1 diabetes who may be at risk for developing the condition themselves.
Not a fit: Patients who do not have a family history of type 1 diabetes or those who have already been diagnosed with diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better management strategies for individuals at risk of developing type 1 diabetes.
How similar studies have performed: Previous research has shown promise in identifying early biomarkers for type 1 diabetes, suggesting that this approach could yield valuable insights.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRUGGEMAN, BRITTANY — UNIVERSITY OF FLORIDA
- Study coordinator: BRUGGEMAN, BRITTANY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases, autoimmune disorder, autoimmunity disease