Understanding muscle recovery after serious illness
Muscle and physical function recovery after acute critical illness
This study is looking at how people who have survived serious illnesses like sepsis and respiratory failure can get their strength and physical abilities back, so we can find ways to help everyone recover better after they leave the hospital.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10930804 on NIH RePORTER |
What this research studies
This research investigates how patients recover muscle and physical function after surviving critical illnesses like sepsis and acute respiratory failure. It focuses on understanding the cellular and clinical factors that affect recovery, using muscle tissue samples and clinical assessments over the first year after hospital discharge. By identifying why some patients regain function while others do not, the study aims to develop better interventions to support recovery and improve quality of life.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have survived critical illnesses such as ARDS or acute respiratory failure.
Not a fit: Patients who have not experienced critical illness or those with pre-existing severe disabilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery strategies for patients who have experienced critical illness, enhancing their quality of life and ability to return to normal activities.
How similar studies have performed: While there is ongoing research in this area, this study's specific approach of combining muscle tissue sampling with clinical assessments is relatively novel.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Dupont-Versteegden, Esther E — University of Kentucky
- Study coordinator: Dupont-Versteegden, Esther E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.