Understanding muscle changes and fat tissue after knee injuries

Skeletal Muscle Remodeling and Intramuscular Adipose Tissue following Traumatic Knee Injury

NIH-funded research University of Utah · NIH-10937920

This study looks at how knee injuries, especially ACL tears, impact your muscles and fat in the body, helping us understand how you heal and when it's safe for you to get back to your favorite activities.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-10937920 on NIH RePORTER

What this research studies

This research investigates how traumatic knee injuries, particularly ACL injuries, affect skeletal muscle and fat tissue in the body. The study aims to explore the cellular changes that occur in muscles and the role of fat cells following such injuries. By utilizing advanced molecular techniques and MRI imaging, the research will provide insights into the healing process and recovery of patients. The findings could help improve clinical decision-making regarding when patients can safely return to physical activities after their injuries.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced an ACL injury or undergone ACL reconstruction.

Not a fit: Patients with knee injuries unrelated to ACL damage or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better recovery protocols and rehabilitation strategies for patients with knee injuries.

How similar studies have performed: Previous research has shown promising results in understanding muscle and fat tissue dynamics after joint injuries, indicating that this approach has potential for success.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions ACL injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.