Understanding muscle and joint recovery after different ACL treatments
Neuromuscular response to competing ACL surgeries
This project looks at how your muscles and joints recover after two different types of ACL surgery, comparing a new healing method to the standard approach.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rhode Island Hospital NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project ID | NIH-11146762 on NIH RePORTER |
What this research studies
We are looking at patients who are part of the BEAR-MOON Trial to understand how their nerves and muscles respond to two different ACL surgeries. One surgery, called BEAR, helps your own torn ligament heal using a special scaffold, keeping your natural nerve connections intact. The other, standard ACL reconstruction (ACLR), replaces the torn ligament with a graft, which means removing some of your original tissue and nerve structures. We want to see if preserving these natural connections with BEAR leads to better muscle recovery and joint movement compared to ACLR, which could help prevent long-term problems like arthritis.
Who could benefit from this research
Good fit: Ideal candidates are individuals who have experienced an ACL injury and are considering or have already participated in the BEAR-MOON Trial.
Not a fit: Patients who have not had an ACL injury or are not candidates for either the BEAR or ACLR procedures would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could help us understand why the newer BEAR procedure might lead to better muscle recovery and joint function, potentially guiding future treatment decisions for ACL injuries.
How similar studies have performed: Early clinical findings suggest that muscle strength may recover better with the BEAR procedure compared to standard ACL reconstruction, and the larger BEAR-MOON Trial is already comparing the two treatments.
Where this research is happening
Providence, United States
- Rhode Island Hospital — Providence, United States (Active)
Researchers
- Principal investigator: Beveridge, Jillian Elizabeth — Rhode Island Hospital
- Study coordinator: Beveridge, Jillian Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.