Understanding mental health and cognitive issues in people living with HIV in Uganda

Mental Health and Cognition in HIV Infection in Rakai Uganda

NIH-funded research Johns Hopkins University · NIH-10663076

This study is looking at how depression and thinking problems affect people living with HIV in Uganda, even when they are getting treatment, and it hopes to find out what specific challenges they face so that better support can be provided.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10663076 on NIH RePORTER

What this research studies

This research investigates the mental health disorders, particularly depression and neurocognitive impairment, that affect individuals living with HIV in Uganda, despite their treatment with antiretroviral therapy. It aims to explore the unique psychosocial factors contributing to these mental health issues in a low-income setting, where common confounding factors seen in wealthier countries are less prevalent. By employing a novel framework that recognizes the diversity of mental health conditions, the study will analyze behavioral phenotypes and their functional consequences. The findings could lead to better-targeted interventions for mental health in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV in Uganda who may be experiencing mental health disorders or cognitive impairments.

Not a fit: Patients living with HIV outside of Uganda or those without mental health concerns may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved mental health care and interventions for individuals living with HIV in Uganda.

How similar studies have performed: Previous research has shown that addressing mental health in HIV populations can lead to significant improvements in patient outcomes, indicating that this approach has potential for success.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.