Understanding kidney disease in patients with sickle cell disease
Official title: Mentoring & Patient-Oriented Research in Sickle Cell-Related Kidney Disease
Funded at University of Illinois at Chicago · NIH-11032270 · Data updated 2026-11-12
This study is all about helping people with sickle cell disease by training new researchers to better understand how it can affect kidney health, so they can find out who is at risk and develop better treatments for kidney problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | December 24, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $137,219 |
| NIH project number | 1K24HL177273-01 |
| Project ID | NIH-11032270 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with sickle cell disease who are at risk for kidney complications.
✕Less likely to help
Patients without sickle cell disease or those who do not have kidney-related issues may not benefit from this research.
What this research studies
This research focuses on improving the understanding of kidney disease related to sickle cell disease (SCD) by training new researchers in this area. It aims to identify high-risk patients and the biological pathways that lead to kidney complications in SCD. The study will involve analyzing genetic factors and their impact on kidney health, particularly how certain genetic variations may predict kidney dysfunction. By fostering collaboration among researchers and clinicians, the project seeks to enhance patient care and develop targeted therapies for those affected.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for kidney disease in patients with sickle cell disease.
How similar studies have gone: Previous research has shown promising results in understanding kidney complications in sickle cell disease, indicating that this approach has potential for success.
Where this research is happening
-
University of Illinois at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Saraf, Santosh — University of Illinois at Chicago
- Study coordinator: Saraf, Santosh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.