Understanding immunity during pregnancy to improve vaccine development

MOMI Administrative Core

NIH-funded research Massachusetts Institute of Technology · NIH-11058425

This study is looking at how pregnancy changes the immune system to help create better vaccines for pregnant people, and it aims to bring researchers together to share information and resources for this important work.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts Institute of Technology NIH-funded
Lab location1 site (Cambridge, United States)
Project IDNIH-11058425 on NIH RePORTER

What this research studies

This research focuses on the unique immunological changes that occur during pregnancy, which have been largely overlooked in immunology. It aims to deeply characterize and investigate how immunity functions in pregnant individuals to inform the development of next-generation vaccines. The program will provide essential administrative and clinical support to facilitate collaboration and data sharing among researchers. By creating platforms for communication and sample access, the initiative seeks to enhance the understanding of how to protect pregnant individuals from infections.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant individuals or those planning to become pregnant who may benefit from enhanced vaccine protection.

Not a fit: Patients who are not pregnant or do not plan to become pregnant may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of vaccines that better protect pregnant individuals from infections, improving maternal and fetal health.

How similar studies have performed: Other research has shown promise in understanding immunological changes during pregnancy, suggesting that this approach could yield significant insights.

Where this research is happening

Cambridge, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autoimmune Diseasesautoimmune disorderautoimmunity diseaseB pertussis infectionB. pertussis infection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.