Understanding immune responses in autoimmune diseases like lupus and type 1 diabetes

Who could benefit from this research

What this research studies

This research focuses on the Immune Epitope Database and Analysis Program, which compiles detailed information about antibodies and T cell epitopes related to autoimmune diseases such as lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myasthenia gravis. It utilizes a vast collection of over 20,500 references to provide insights into how the immune system interacts with these diseases. Patients can benefit from the tools developed to predict and visualize epitopes, which may lead to better-targeted therapies and improved understanding of their conditions.

Why it matters

Where this research is happening

• La Jolla Institute for Immunology
  La Jolla, United States Active

Researchers

• Principal investigator: Sette, Alessandro — La Jolla Institute for Immunology
• Study coordinator: Sette, Alessandro

Related research

Other NIH-funded projects on the same topics.

• Understanding immune responses in autoimmune diseases

  This study is all about gathering and sharing information on how our immune system reacts in autoimmune diseases like lupus and rheumatoid arthritis, so that patients can benefit from better understanding and treatment options.

  NIH research La Jolla Institute for Immunology · La Jolla, United States · NIH-11041926

• Understanding immune responses in autoimmune diseases like lupus and diabetes

  This study is looking at how certain immune system parts, like antibodies and T cell pieces, relate to autoimmune diseases such as lupus and rheumatoid arthritis, to help find better treatments and understand these conditions more clearly for patients.

  NIH research La Jolla Institute for Immunology · La Jolla, United States · NIH-10788230

• Understanding immune responses in autoimmune diseases

  This study is all about gathering and sharing information on how our immune system works with autoimmune diseases like lupus and rheumatoid arthritis, so that patients can better understand their conditions and how to manage them.

  NIH research La Jolla Institute for Immunology · La Jolla, United States · NIH-10551167

• Gut microbes and methotrexate: boosting RA treatment through microbiome targets

  Researchers are studying how gut bacteria affect how well methotrexate works for people with rheumatoid arthritis, aiming to make MTX effective for more patients.

  NIH research Veterans Affairs Med Ctr San Francisco · San Francisco, United States · NIH-11606746

• Technological and Educational Approaches to Restore Hypoglycemia Awareness in Type 1 Diabetes

  A two-arm study in adults with type 1 diabetes tests whether high-tech glucose control plus education or targeted training can help people regain awareness of low blood sugar.

  NIH research University of Sheffield · Sheffield, United Kingdom · NIH-11603070

• Techniques for restoring awareness of low blood sugar in adults with type 1 diabetes

  A randomized trial compares different approaches to help adults with type 1 diabetes recognize when their blood sugar is dipping so they can act quickly.

  NIH research University of Sheffield · Sheffield, United Kingdom · NIH-11603069

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.