Understanding immune responses in autoimmune diseases like lupus and type 1 diabetes
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Autoimmune diseases, including SLE, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myathenia gravis
This study is all about gathering helpful information on how our immune system works with autoimmune diseases like lupus and rheumatoid arthritis, so that patients can get better treatments and a clearer understanding of their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | La Jolla Institute for Immunology NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10021128 on NIH RePORTER |
What this research studies
This research focuses on the Immune Epitope Database and Analysis Program, which compiles detailed information about antibodies and T cell epitopes related to autoimmune diseases such as lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myasthenia gravis. It utilizes a vast collection of over 20,500 references to provide insights into how the immune system interacts with these diseases. Patients can benefit from the tools developed to predict and visualize epitopes, which may lead to better-targeted therapies and improved understanding of their conditions.
Who could benefit from this research
Good fit: Ideal candidates include individuals diagnosed with autoimmune diseases such as lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, or myasthenia gravis.
Not a fit: Patients with non-autoimmune conditions or those not diagnosed with the specified autoimmune diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for autoimmune diseases by identifying specific immune responses.
How similar studies have performed: Previous research has shown success in utilizing epitope mapping and analysis tools to enhance understanding and treatment of autoimmune diseases.
Where this research is happening
La Jolla, United States
- La Jolla Institute for Immunology — La Jolla, United States (Active)
Researchers
- Principal investigator: Sette, Alessandro — La Jolla Institute for Immunology
- Study coordinator: Sette, Alessandro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.