Understanding immune responses in autoimmune diseases like lupus and diabetes
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Autoimmune diseases, including SLE, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myathenia gravis
['FUNDING_OTHER'] · LA JOLLA INSTITUTE FOR IMMUNOLOGY · NIH-10788230
This study is looking at how certain immune system parts, like antibodies and T cell pieces, relate to autoimmune diseases such as lupus and rheumatoid arthritis, to help find better treatments and understand these conditions more clearly for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LA JOLLA INSTITUTE FOR IMMUNOLOGY (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10788230 on ClinicalTrials.gov |
What this research studies
This research focuses on the Immune Epitope Database and Analysis Program, which compiles detailed information about antibodies and T cell epitopes related to autoimmune diseases such as lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myasthenia gravis. By analyzing over 20,500 curated references, the program aims to predict and visualize how these immune components interact with proteins in the body. Patients can benefit from insights that may lead to better-targeted therapies and improved understanding of their conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with autoimmune diseases such as lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, or myasthenia gravis.
Not a fit: Patients with non-autoimmune conditions or those not diagnosed with the specified autoimmune diseases may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for autoimmune diseases by identifying specific immune responses.
How similar studies have performed: Previous research has shown success in utilizing epitope analysis to improve understanding and treatment of autoimmune diseases, indicating that this approach is promising.
Where this research is happening
LA JOLLA, UNITED STATES
- LA JOLLA INSTITUTE FOR IMMUNOLOGY — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WILSON, STEPHEN — LA JOLLA INSTITUTE FOR IMMUNOLOGY
- Study coordinator: WILSON, STEPHEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases, autoimmune disorder, autoimmunity disease, Insulin-Dependent Diabetes Mellitus, Brittle Diabetes Mellitus