Understanding immune responses in autoimmune diseases like lupus and diabetes
Official title: IMMUNE EPITOPE AND ANALYSIS PROGRAM: Autoimmune diseases, including SLE, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myathenia gravis
Funded at La Jolla Institute for Immunology · NIH-10788230 · Data updated 2026-11-12
This study is looking at how certain immune system parts, like antibodies and T cell pieces, relate to autoimmune diseases such as lupus and rheumatoid arthritis, to help find better treatments and understand these conditions more clearly for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | La Jolla Institute for Immunology NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | December 15, 2018 |
| Project end | December 14, 2025 |
| Funding year | 2023 |
| Award (this year) | $32,094 |
| NIH project number | 75N93019C00001-P00014-9999-3 |
| Project ID | NIH-10788230 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with autoimmune diseases such as lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, or myasthenia gravis.
✕Less likely to help
Patients with non-autoimmune conditions or those not diagnosed with the specified autoimmune diseases may not receive any benefit from this research.
What this research studies
This research focuses on the Immune Epitope Database and Analysis Program, which compiles detailed information about antibodies and T cell epitopes related to autoimmune diseases such as lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myasthenia gravis. By analyzing over 20,500 curated references, the program aims to predict and visualize how these immune components interact with proteins in the body. Patients can benefit from insights that may lead to better-targeted therapies and improved understanding of their conditions.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for autoimmune diseases by identifying specific immune responses.
How similar studies have gone: Previous research has shown success in utilizing epitope analysis to improve understanding and treatment of autoimmune diseases, indicating that this approach is promising.
Where this research is happening
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La Jolla Institute for Immunology
La Jolla, United States Active
Researchers
- Principal investigator: Wilson, Stephen — La Jolla Institute for Immunology
- Study coordinator: Wilson, Stephen
Related research
Other NIH-funded projects on the same topics.
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Understanding immune responses in autoimmune diseases
This study is all about gathering and sharing information on how our immune system reacts in autoimmune diseases like lupus and rheumatoid arthritis, so that patients can benefit from better understanding and treatment options.
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Understanding immune responses in autoimmune diseases
This study is all about gathering and sharing information on how our immune system works with autoimmune diseases like lupus and rheumatoid arthritis, so that patients can better understand their conditions and how to manage them.
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Understanding immune responses in autoimmune diseases like lupus and type 1 diabetes
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.