Understanding immune responses in autoimmune diseases
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Autoimmune diseases, including SLE, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myathenia gravis
This study is all about gathering and sharing information on how our immune system reacts in autoimmune diseases like lupus and rheumatoid arthritis, so that patients can benefit from better understanding and treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | La Jolla Institute for Immunology NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11041926 on NIH RePORTER |
What this research studies
This research focuses on the Immune Epitope Database and Analysis Program, which compiles detailed information about antibodies and T cell epitopes related to autoimmune diseases such as lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myasthenia gravis. It utilizes extensive literature and data from NIAID contractors to curate over 20,500 references, providing tools for predicting and visualizing epitopes. Patients can benefit from the insights gained through this program, which aims to enhance understanding of immune responses and potentially lead to better treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with autoimmune diseases like lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, or myasthenia gravis.
Not a fit: Patients with non-autoimmune conditions or those not diagnosed with the specified autoimmune diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for patients with autoimmune diseases.
How similar studies have performed: Previous research has shown success in utilizing epitope mapping and analysis for understanding autoimmune diseases, indicating that this approach is promising.
Where this research is happening
La Jolla, United States
- La Jolla Institute for Immunology — La Jolla, United States (Active)
Researchers
- Principal investigator: Wilson, Stephen — La Jolla Institute for Immunology
- Study coordinator: Wilson, Stephen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.