Understanding immune cells and pathways involved in autoimmune diseases
Immune Cells and Secretory Pathways Leading to Human Systemic Autoimmunity
This study is looking at how certain immune cells and tiny particles in the body can cause autoimmune diseases like Systemic Lupus Erythematosus (SLE) in children, with the goal of creating better ways to track these issues and tailor treatments for patients of all ages.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11080339 on NIH RePORTER |
What this research studies
This research investigates the mechanisms and pathways that lead to systemic autoimmune diseases, focusing on how immune cells and extracellular nanoparticles contribute to these conditions. The team at Weill Cornell Medicine aims to develop tools and biomarkers that can help monitor these dysfunctional pathways, ultimately allowing for personalized treatment approaches. The research will initially focus on children with Systemic Lupus Erythematosus (SLE) but will also explore implications for adults and other autoimmune diseases. By utilizing advanced technologies in immune profiling and cell biology, the study seeks to enhance our understanding of autoimmune conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adults diagnosed with systemic autoimmune diseases, particularly Systemic Lupus Erythematosus.
Not a fit: Patients with non-autoimmune conditions or those not diagnosed with systemic autoimmune diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for patients with autoimmune diseases.
How similar studies have performed: Previous research has shown promise in understanding autoimmune diseases through similar approaches, indicating potential for success in this area.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Pascual, Maria Virginia — Weill Medical Coll of Cornell Univ
- Study coordinator: Pascual, Maria Virginia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.