Understanding how Wnt signaling affects different cell types in Hydra.
Official title: Solving cell-type specific differences of the Wnt-directed gene regulatory network in Hydra vulgaris.
Funded at University of California at Davis · NIH-10904676 · Data updated 2026-11-12
This study looks at how a specific signaling pathway affects the growth of different cell types in the Hydra, a small water creature, to help us understand important biological processes that could relate to development and diseases.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | July 3, 2023 |
| Project end | July 2, 2025 |
| Funding year | 2024 |
| Award (this year) | $41,568 |
| NIH project number | 5F31GM149176-02 |
| Project ID | NIH-10904676 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be individuals interested in developmental biology or those affected by conditions related to Wnt signaling.
✕Less likely to help
Patients with conditions unrelated to developmental biology or Wnt signaling may not receive any benefit from this research.
What this research studies
This research investigates how the Wnt signaling pathway influences the development of various cell types in the organism Hydra vulgaris. By examining the unique responses of different cell types to Wnt signals, the study aims to uncover the gene regulatory networks that are activated in these contexts. The approach involves advanced techniques like ATAC sequencing to analyze chromatin accessibility and gene expression patterns. This research could provide insights into fundamental biological processes that are relevant to developmental biology and disease.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of developmental processes and potentially inform treatments for diseases related to Wnt signaling dysregulation.
How similar studies have gone: While the specific approach in this research is novel, studies on Wnt signaling have shown success in understanding developmental processes in other organisms.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Morris Little, Hannah — University of California at Davis
- Study coordinator: Morris Little, Hannah
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.