Understanding how visual perception works in schizophrenia
Official title: Visual perception in schizophrenia: assessing predictive processing in the earliest stages of the visual cortical hierarchy
Funded at University of Rochester · NIH-11125156 · Data updated 2026-11-12
This study is looking at how people with schizophrenia see and understand visual information differently than those without the condition, and it aims to learn more about how this might relate to experiences like hallucinations and delusions, involving both healthy individuals and those with schizophrenia or bipolar disorder.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | May 5, 2025 |
| Project end | May 4, 2027 |
| Funding year | 2025 |
| Award (this year) | $423,500 |
| NIH project number | 1R21MH140245-01 |
| Project ID | NIH-11125156 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with schizophrenia or bipolar disorder, as well as healthy volunteers for comparison.
✕Less likely to help
Patients who do not have schizophrenia or bipolar disorder may not receive direct benefits from this research.
What this research studies
This research investigates how individuals with schizophrenia perceive visual information and how this process may differ from those without the disorder. By using innovative visual stimuli and measuring brain responses through EEG, the study aims to explore the role of predictive processing in visual perception. The goal is to understand how hallucinations and delusions may arise from misinterpretations of sensory information. Participants will include healthy individuals, those with schizophrenia, and patients with bipolar disorder, allowing for a comprehensive comparison of visual processing across these groups.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for visual perception issues in schizophrenia and related disorders.
How similar studies have gone: Previous research has indicated that understanding predictive processing in perception can provide valuable insights into psychotic disorders, suggesting potential for success in this approach.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Lalor, Edmund — University of Rochester
- Study coordinator: Lalor, Edmund
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.